Welcome to the Bioinformatics Toolkit
Most frequently used tools
August, 2015Tool HMMER3 now uses hmmer 3.1.b2 instead of hmmer 3.0 Added new tools PSI-BLAST+ and ProtBLAST+, similar to tools PSI-BLAST/ProtBLAST. The new tools use BLAST+ programs while tools PSI-BLAST/ProtBLAST continue to use legacy BLAST. These currently are kept because we observed big differences in the output of the new tools with some use cases.
July, 2015Bioprogs called by some tools were updated to a newer version: MAFFT, TCoffee, Modeller, Muscle, Phylip-Neighbor.
May, 2015To improve the toolkit experience with browsers not supporting java applets, tools Modeller and bFit now use JSmol for displaying pdb structures.
November, 2014scop 1.75 databases were replaced by SCOPe 2.04 databases.
June, 2013The signal peptide identification protocol Predisi has been added to Quick2D.
April, 2013The sequence alignment tool MSAProbs has been added to our library of programs.
April, 2013Clustal Omega has been made default for the clustal alignment protocol .
Alternative Toolkit Location
Reference: Biegert A, Mayer C, Remmert M, Söding J and Lupas A. The MPI Toolkit for protein sequence analysis Nucleic Acids Res. 34, W335-339 (download pdf)