Four-helical bundle analysis tool


1GCL paste/results   2R2V paste/results  
(Example results have been precomputed at some time. They most probably are not identical to results of a new computation with actualized databases.)

Input parameters (obligatory)

Note: The helices need to be entered according to their sequential position
in the bundle (it is not relevant whether this done clockwise or counterclockwise,
and whether one starts with the N-terminal helix or any other one), and not in
their order from N- to C-terminus. For helices in anti-parallel orientation, the residue
range should be given with the larger residue number before the smaller one.

Definition for helix 1
first position chain from to 
Definition for helix 2
first position chain from to 
Definition for helix 3
first position chain from to 
Definition for helix 4
first position chain from to 

Job Options

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References (please cite as appropriate)

Alva V., Nam SZ., Söding J., Lupas AN. (2016) The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis. Nucleic Acids Res. pii: gkw348. [Epub ahead of print] PMID: 27131380
Dunin-Horkawicz S., Lupas AN. (2010) Measuring the conformational space of square four-helical bundles with the program samCC. 170(2):226-35. doi: 10.1016/j.jsb.2010.01.023. PMID: 20139000


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